Aiming at the problem of the construction of integrated defense system in key areas, a solution of integrated defense system in key areas is proposed. On the basis of drawing lessons from the development of the US army and analyzing the development needs of our army, the composition, function and characteristics of the system are expounded, and the defense combat process based on typical key area is analyzed. The analysis results show that the plan can form the equipment and combat capability in a short time, provide comprehensive defense support for our army in all directions and the whole process, and provide reference for the construction of integrated defense system in key areas of our country.