In view of the complex battlefield environment, diversified combat targets and complex interference environment, the anti-interference capability and key technical requirements of anti-armor missile are analyzed. This paper analyzes the interference threat, characteristics and deficiency of anti-interference of anti-armor missile seeker, and gives some relevant measures and suggestions to improve anti-interference ability of anti-armor missile seeker scientifically and efficiently. The results show that the analysis can provide reference for improving anti-jamming ability of anti-armor seeker.