Starting with the missile trajectory simulate for prearranged guidance rule targets supposed, analyze rationally killing points of missile versus target which satisfy killing factors, and then establish the killing zone database. Analyze the relativity between the trajectory characteristics of antiaircraft missile and killing zone of the weapon, simulate some representative targets movements, model the missile guide contrail systematically which to hit the target. Taking the proportion guide trajectory as an example to simulate the process, receive a group of killing zone data suitable to a given target, which is important to the weapon effectiveness evaluation.