In order to obtain reliable and accurate environment information, adopt multi-sensor information fusion technology. Introduce the unmanned platform obstacle avoidance system composition, obstacle avoidance information processing and obstacle avoidance control model and strategy. Through data fusion for ultrasonic sensor, infrared sensor and other sensors, research on application of multi-sensor information fusion technology in unmanned platform automatic obstacle avoidance. The test result shows that the technology can achieve unmanned platform accurately, avoid obstacles in high speed. It provides a technology for unmanned platform working in intricate, dynamic, uncertain or unknown environment.