In order to eliminate subjective differences in product detected by human eyes, machine vision was used in chromatic aberration detection of industrial products. Chromatic aberration detection system was used to compute chromatic aberration between product appearance and standard color board. The images contain product and standard color board were captured through industrial CCD camera under uniform illumination. At last, compare chromatic aberration with threshold to determine whether the product is up to standard. The system uses CIEDE2000 color difference formula which can reflect minor differences in color correctly. The experiment results indicate that the testing result has a good consistance with human eyes and the feasibility of this method is proved.