To meet the demand of rapid support, optimization of technical preparation procedure for a certain missile was analyzed through program evaluation and review technique (PERT) simulation. Meanwhile, Activity criticality index (ACI) and crucial index (CRI) of each activity were led into for quantitative evaluation of effect on completion. Effects of optimization were forecasted accurately and project completion probability and index value of quantitative evaluation for activities were obtained by simulating. The result indicates that technical preparation time was shortened greatly by optimizing, and effect of optimization can be forecasted accurately. Reasonable method and references for control of schedule plan are provided.