To obtain a larger basic ammunition and improve the combat capability of caliber, discuss the spiral guidance design of ammunition feed system. This paper established the mathematical model of spiral guidance and use solidworks software for 3D modeling, established muti-body dynamics model of the spiral guidance in ADAMS software. The simulation results show: the resistance of this spiral guidance is not great, shells can be smoothly passed, verify the feasibility of this design method. Provide a new way for the structural design of ammunition feed system.