Aiming at the features of long running time, complex system structure and high safety requirement of continuous wind tunnel equipment, establish safety interlock system. Use ProfiNet real time Ethernet as network platform, establish safety interlock system structure, design and realize continuous wind tunnel signal monitoring and safety interlock control function by mutual redundancy of software and hardware. Use loop network technology to improve network transmission reliability, adopt hierarchical multilevel interlock technology to make data transmission better, effectively improve efficiency of wind tunnel. The analysis results show that: the system has advantages of simple structure and stability, it can totally satisfy safety running monitoring requirement of continuous wind tunnel.