Aiming at the problems of inconvenience of erecting and the independence of cooperation targets that have the problems with large volume and high-power in the calibration devices of landing guidance system and with the needs of the calibration based on UAV, the small size and light power embedding a calibration system based on the unmanned aerial vehicles (UAV) is put forward. The paper uses the embedded software and hardware technology to design the project, analyzing and completing the integrating the cooperation system of the guidance system. The results of the research indicate that the system works with unify-time under the control of the ARM chip processor and has high practical value. The paper opens up new ideas for the calibration based on UAV.