In view of the lack of research on the anti-interference performance of PN code and pulse-Doppler combined fuse, the anti-interference performance of this fuse under white Gaussian noise (GWN) condition is studied. Based on analyzing of the working principle and anti-interference principle of this fuse and using the modular programming method in LabVIEW, the anti-GWN interference simulation results of PN code and pulse-Doppler combined fuse related demodulated signals with different symbol width and PN code length are obtained. The results show that the anti-interference of the PN code and pulse-Doppler combined fuse is affected by the symbol width and the PN code length. The narrower the symbol width, the longer the PN code length, the better the anti-interference effect.