In order to solve the starting fault of the minimum system board, a starting optimization method is proposed. By analyzing the power failure, reset abnormal, clock instability, startup configuration failure, initialization abnormal and other factors, the system initialization failure and abnormal cause the failure of not starting and slow starting. It can be seen from the following initialization signal detection, check SDRAM refresh cycle control register, startup time and MPTPR test three steps: the minimum system board startup failure is due to the failure to initialize the register MPTPR in the underlying driver BIOS, and re-optimize the startup control flow chart. The results show that the optimization measures are reasonable and effective, and the startup failure is solved.