In order to control the charge quality of large equivalent DNAN-base melt cast explosive in charge technology, this paper puts forward a charge quality control method for cast explosive. Analyzing reasons for charge defects, this paper designs charge technology based on the structural characteristics of product, and eliminates charge problems and defects with measures for controlling technological process. ANSYS software is used to conduct simulation computation on cast loading method, getting a set of best technological parameter which is verified though the application of typical products. The application results demonstrate that this method has eliminated defects such as charge shrinkage void and crack, the total weight of product conforms to index requirement, and that the charge quality has been improved obviously.