The numerical simulation for the process of the jet penetration through the moving steel target was carried out, and the influence of explosive characteristic, blasting height and the steel target velocity on jet penetration process was comparative analyzed. And the destructive feature of poly-energy jet penetrating moving steel target was analyzed. The simulation results show that the higher velocity of the moving steel target can cause a greater velocity loss after jet penetration. In order to keep the ability of shaped charge jet penetrating the target with high speed, it’s suggested that adopt high explosives as shaped charge and design a reasonable blasting height.