In order to obtain the dynamic response law of projectile explosive charge, a certain type of naval gun is taken as the prototype, and the original scale modeling is established by LS-DYNA. The process of penetration into concrete target plate was simulated by building 2 kinds of projectile models of cylindrical and truncated cone-shaped charging modes, and the stress curve of explosive charge and the pressure curve of explosive detonation were obtained. The results show that the cylindrical charge projectile does not penetrate the target completely and early burst occurs. The truncated cone-shaped projectile completely penetrated the target plate without detonation. The simulation results show that the truncated cone-shaped charge can effectively reduce the collision probability between the charge and the shell, and improve the penetration safety.