In order to improve the sampling efficiency and safety of solid rocket motor, a numerical control sampling system for solid rocket motor was developed. Taking an engine combustor as the research object, the safe operation methods of outer wall milling and sensitive material cutting are obtained by the key technologies of milling feed compensation based on contour dimension detection and cutting sampling based on multi-parameter coupling. Combined with the automatic control technology, the existing sampling process is optimized and improved, and the safety protection measures are put forward, and the experimental verification is carried out. The results show that the system satisfies the specific technical indexes and can realize numerical control safety sampling of solid rocket motor.