In view of the development trend of future air defense combat situation, combined with the development status of effectiveness evaluation mode at home and abroad, the problem of multi-target interception by multi-firepower units suitable for actual combat is studied in depth. A scientific and reasonable evaluation index system is established. Based on the fuzzy multi-objective decision theory, the operational plan is sorted and analyzed by using the method of combining qualitative analysis with quantitative calculation, and the optimal operational plan is determined. The example results show that the method is effective.