In order to solve the problems of different data formats of medical equipment and single function of telemedicine system, a telemedicine monitoring system based on embedded system is proposed. The structure of the telemedicine monitoring system is designed, which is composed of a multi-parameter acquisition system and an ARM-based embedded computer system. The software layer of the telemedicine monitoring system based on embedded system is designed, which can be divided into data acquisition module, network communication module and analysis module according to its function; In the experimental stage, a simulation system is used to verify the effectiveness of the proposed scheme. The experimental results show that the measurement errors of electrocardiogram (ECG) and blood pressure are within ± 5%, and the measurement errors of all parameters are within the standard error range. The simulation results verify that the proposed embedded telemedicine system provides a reference for the development of health care system and the improvement of service quality.