Air-conditioning system is mainly used for textile manual control of the situation, a new temperature and humidity control system based on PROFIBUS-DP is proposed. Taking Xinjiang Aksu Juying textile mill as example, give the overall system control program, the system is divided into Field equipment, equipment control layer and management control structure layer, and explains the detail of the system software and hardware design. The results show that the system can not only improve the system stability and efficiency, but also temperature and humidity control to achieve the whole process of real-time monitoring and management.