For realize the precise adjustment of touch screen, introduce algorithm of touch screen multi-points collection based on MiniGUI in embedded Linux system. The algorithm use MiniGUI timer information and mouse information. Adopt 5 basic object points in screen adjustment program, and value collection of every objection point is divided into multi cursor point’s calculation. Through multi-point data collection, comparison and processing, the touch screen can precisely adjust. The result shows that the algorithm can collect more correct value, and less error operations in processing.