Aiming at the accidents, serious pollution problems and low yields in single explosive production process, use automation production process and computer control technology. In dangerous situations, use intrinsically safe control technology and medicine waste collection techniques. It realizes automated production of the explosive compound and washing unit, reduces the manual operation, eliminates insecurity of the flammable and explosive in explosive production, and increases production. The results show that: the production line has a reasonable structure, enabling man-machine isolation, reduces the number of operators and increase output, eliminates security risks to meet the automated production process.